Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Sacubitrilat-d4 is the deuterium labeled Sacubitrilat. Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor. This compound is for research use only and not sold to patients.
Can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Deuterium substitution: stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Purity: 99.28%
Appearance: solid, white to off-white.
Solubility: soluble in DMSO at 100 mg/mL (258.09 mM).
Storage: powder at -20°C for 3 years or 4°C for 2 years. In solvent at -80°C for 6 months or -20°C for 1 month.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An analog of D-erythro-sphingosine; inhibits PKC in mixed micelle assays with 50% inhibition at 2.2 mol % making it a more potent inhibitor compared to D-erythro-sphingosine or other analogs of shorter alkyl chain length
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Maxacalcitol-d6 is the deuterated form of maxacalcitol (22-oxacalcitriol), a non-calcemic vitamin D3 analog and vitamin D receptor (VDR) ligand used as a labeled reference standard for research. It is supplied as a high-purity solid (99.63%) in a 10 mg pack and is intended for analytical applications including mass spectrometry, pharmacokinetic studies, and VDR pathway research.
Deuterated internal standard for quantitative mass spectrometry.
Non-calcemic vitamin D3 analog and VDR ligand.
High purity (99.63%) suitable for analytical and bioanalytical assays.
Solid white to off-white form with good stability under recommended storage.
Supplied in 10 mg packs for laboratory use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
D18 is an immune modulator and acts as a TLR7/8 dual agonist. It increases PD-L1 expression through epigenetic regulation, sensitizing tumors to PD-1/PD-L1 blockade. This substance is also an ADC cytotoxin used for the synthesis of ADC HE-S2 (HY-144497) and exhibits strong immune activation and anti-tumor activity, commonly used in cancer research.
Acts as a TLR7/8 dual agonist
Increases PD-L1 expression through epigenetic regulation
Sensitizes tumors to PD-1/PD-L1 blockade
Utilized as an ADC cytotoxin for ADC HE-S2 synthesis
Exhibits strong immune activation and anti-tumor activity
Used in cancer research, including colon cancer
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Pirenzepine-d8 dihydrochloride is a deuterium-labeled version of Pirenzepine dihydrochloride. It acts as a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist, reducing gastric acid secretion and muscle spasms. This makes it useful in peptic ulcer research and it also shows anti-proliferative activity against cancer cells.
Deuterium labeled compound.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes are incorporated for quantitation during drug development.
Potential to affect pharmacokinetic and metabolic profiles of drugs due to deuteration.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More